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Disease Classifications
Class A Diseases
Diseases of major public health concern because of the severity of disease or potential for epidemic spread • report by telephone immediately upon recognition that a case, a suspected case, or a positive laboratory result exists
| Anthrax |
Rabies, human |
| Botulism, foodborne |
Rubella (not congenital) |
| Cholera |
Severe Acute Respiratory Syndrome (SARS) |
| Diphtheria |
Smallpox |
| Influenza A - novel virus |
Tularemia |
| Measles |
Viral hemorrhagic fever (VHF) |
| Meningococcal disease |
Yellow fever |
| Plague |
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Any unexpected pattern of cases, suspected cases, deaths or increased incidence of any other disease of major public health concern, because of the severity of disease or potential for epidemic spread, which may indicate a newly recognized infectious agent, outbreak, epidemic, related public health hazard or act of bioterrorism.
Class B Diseases (1)
Diseases of pubic health concern needing timely response because of potential for epidemic spread • report by the end of the next business day after the existence of a case, a suspected case, or a positive laboratory result is known
Arboviral neuroinvasive and non-neuroinvasive disease
- Eastern equine encephalitis virus disease
- LaCrosse virus disease (other California serogroup virus disease)
- Powassan virus disease
- St. Louis encephalitis virus disease
- West Nile virus infection
- Western equine encephalitis virus disease
- Other arthropod-borne disease |
| Chancroid |
| Coccidioidomycosis * |
| Cyclosporiasis |
| Dengue |
| E. coli O157:H7 and other enterohemorrhagic (Shiga toxin-producing) E. coli |
| Granuloma inguinale |
| Haemophilus influenzae (invasive disease) |
| Hantavirus |
| Hemolytic uremic syndrome (HUS) |
| Hepatitis A |
| Hepatitis B, perinatal |
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| Influenza-associated pediatric mortality |
| Legionnaires’ disease |
| Listeriosis |
| Malaria |
| Meningitis, aseptic (viral) |
| Meningitis, bacterial |
| Mumps |
| Pertussis |
| Poliomyelitis (including vaccine-associated cases) |
| Psittacosis |
| Q fever |
| Rubella (congenital) |
| Salmonellosis |
| Shigellosis |
| Staphylococcus aureus, with resistance or intermediate resistance to Vancomycin (VRSA, VISA) |
| Syphilis |
| Tetanus |
| Tuberculosis, including multi- drug resistant tuberculosis (MDR-TB) |
| Typhoid fever |
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Class B Diseases (2)
Diseases of significant public health concern • report by the end of the work week after the existence of a case, a suspected case, or a positive laboratory result is known
| Amebiasis |
| Botulism, infant |
| Botulism, wound |
| Brucellosis |
| Campylobacteriosis |
| Chlamydia infections (urethritis, epididymitis, cervicitis, pelvic inflammatory disease, neonatal conjunctivitis, pneumonia, and lymphogranuloma venereum (LGV)) |
| Creutzfeldt-Jakob disease (CJD) |
| Cryptosporidiosis |
| Cytomegalovirus (CMV) (congenital) |
| Ehrlichiosis/Anaplasmosis |
| Giardiasis |
| Gonococcal infections (urethritis, cervicitis, pelvic inflammatory disease, pharyngitis, arthritis, endocarditis, meningitis and neonatal conjunctivitis) |
| Hepatitis B, non perinatal |
| Hepatitis C |
| Hepatitis D (delta hepatitis) |
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| Hepatitis E |
| Herpes (congenital) |
| Influenza-associated hospitalization |
| Leprosy (Hansen disease) |
| Leptospirosis |
| Lyme disease |
| Mycobacterial disease, other than tuberculosis (MOTT) |
| Rocky Mountain spotted fever (RMSF) |
| Streptococcal disease, group A, invasive (IGAS) |
| Streptococcal disease, group B, in newborn |
| Streptococcal toxic shock syndrome (STSS) |
| Streptococcus pneumoniae, invasive disease (ISP) |
| Toxic shock syndrome (TSS) |
| Trichinosis |
| Typhus fever |
| Varicella |
| Vibriosis |
| Yersiniosis |
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Class C Diseases
Report an outbreak, unusual incidence, or epidemic (e.g., histoplasmosis, pediculosis, scabies, staphylococcal infections) by the end of the next working day
| Outbreaks: |
| Community |
| Foodborne |
| Healthcare-associated |
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| Outbreaks: |
| Institutional |
| Waterborne |
| Zoonotic |
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Updated August 2009
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